Moderate riskAfrica · Eastern AfricaMayotte Travel Health Guide
Moderate risk
Mayotte carries a CDC Level 1 travel health notice. Malaria risk exists in Mayotte. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Overall risk
Moderate risk
Malaria
Present
Best time to visit
Year-round
Recommended vaccines
Routine Vaccines
Make sure all routine vaccines are up to date including chickenpox, tetanus, flu, MMR, polio, and shingles.
COVID-19
Stay up to date with COVID-19 vaccines before traveling.
Hepatitis A
Hepatitis A vaccine is recommended for all unvaccinated travelers 1 year and older. Infants 6-11 months should also get vaccinated.
Hepatitis B
Hepatitis B vaccine is recommended for all unvaccinated travelers of any age going to Mayotte.
Measles
All travelers should be fully vaccinated against measles with MMR vaccine at least 2 weeks before travel. Infants 6-11 months need an early dose.
Typhoid
Typhoid vaccine is recommended for most travelers, especially if visiting rural areas or staying with friends and relatives.
Chikungunya
Chikungunya vaccine is generally not recommended. Focus on preventing mosquito bites instead.
Cholera
Cholera vaccine is not recommended as there is no active cholera transmission in Mayotte.
Rabies
Rabies-infected dogs are not common in Mayotte. Consider pre-exposure vaccination if you'll have high-risk animal contact or limited access to medical care.
Yellow Fever
Yellow fever vaccine is not recommended for disease prevention. However, it's required for entry if coming from countries with yellow fever risk or transit >12 hours through such countries.
Disease risks
Malaria risk
Malaria is present in this destination. Prophylaxis medication is recommended.
Malaria risk exists in Mayotte. Take antimalarial medication as prescribed and continue taking it after returning home.
Emergency numbers
Police
17
Medical / Ambulance
15
Fire
18
U.S. Embassy
+33-1-43-12-22-22
Mayotte travel health FAQ
Do I need vaccines to travel to Mayotte?▼
For travel to Mayotte, Routine Vaccines, COVID-19, Hepatitis A, Hepatitis B, Measles and Typhoid are recommended; Chikungunya, Cholera, Rabies and Yellow Fever may be advised depending on your itinerary. Make sure your routine vaccinations (such as MMR, Tdap, polio and seasonal flu) are up to date, and see a travel-health provider about 4–6 weeks before you leave.
Is there malaria in Mayotte?▼
Yes — malaria is present in Mayotte. Antimalarial prophylaxis is recommended for most travelers, alongside insect-bite precautions such as repellent and treated bed nets.
Is it safe to travel to Mayotte?▼
From a travel-health standpoint, Mayotte is currently rated moderate risk. Mayotte carries a CDC Level 1 travel health notice. Malaria risk exists in Mayotte. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
What are the emergency phone numbers in Mayotte?▼
Key emergency numbers in Mayotte are Police 17, Medical / Ambulance 15, Fire 18 and U.S. Embassy +33-1-43-12-22-22. Save them before you travel and confirm the current numbers with your accommodation on arrival.
More country guides
British Indian Ocean TerritoryLow riskBritish Indian Ocean Territory carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
BurundiHigh riskBurundi carries a CDC Level 1 travel health notice. Malaria risk exists throughout Burundi year-round. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
ComorosHigh riskComoros carries a CDC Level 1 travel health notice. Malaria risk exists throughout Comoros. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.