Cambodia Travel Health Guide
Moderate risk
Cambodia carries a CDC Level 1 travel health notice. Malaria risk exists primarily in rural and forested areas of Cambodia. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Overall risk
Moderate risk
Malaria
Present
Best time to visit
Year-round
Recommended vaccines
Routine vaccines
Make sure all routine vaccines are up to date, including chickenpox, tetanus, flu, MMR, polio, and shingles vaccines.
COVID-19
Stay up to date with COVID-19 vaccines before traveling.
Hepatitis A
Hepatitis A vaccine is recommended for all travelers to Cambodia who haven't been vaccinated. Even infants 6-11 months should get vaccinated.
Hepatitis B
Hepatitis B vaccine is recommended for travelers under 60. Those 60 and older may choose to get vaccinated.
Measles
All travelers should be fully vaccinated against measles with MMR vaccine, including infants 6-11 months who need an early dose.
Typhoid
Typhoid vaccine is recommended for most travelers to Cambodia, especially if staying with locals or visiting smaller cities and rural areas.
Chikungunya
Chikungunya vaccine is generally not recommended. Focus on preventing mosquito bites instead.
Japanese Encephalitis
Japanese encephalitis vaccine is recommended if you're staying long-term, frequently traveling to the area, or doing outdoor activities in rural areas without proper protection from mosquitoes.
Rabies
Rabies-infected dogs are common in Cambodia. Consider pre-exposure vaccination if you'll be doing activities that increase animal exposure or might have difficulty getting prompt medical care.
Yellow Fever
Yellow fever vaccine is not recommended for Cambodia itself, but is required for entry if you're coming from a country with yellow fever risk, including airport layovers over 12 hours.
Disease risks
Malaria
Malaria risk exists primarily in rural and forested areas of Cambodia. No risk in major cities like Phnom Penh, Siem Reap, or Angkor Wat. Take antimalarial medication if visiting rural/forested areas.
Traveler's Diarrhea
All areas except Phnom Penh; high risk from local food and water.
Malaria risk
Malaria is present in this destination. Prophylaxis medication is recommended.
Malaria risk exists primarily in rural and forested areas of Cambodia. No risk in major cities like Phnom Penh, Siem Reap, or Angkor Wat. Take antimalarial medication if visiting rural/forested areas.
Emergency numbers
Police
117
Medical / Ambulance
119
Fire
118
U.S. Embassy
+855-23-728-000
Cambodia travel health FAQ
Do I need vaccines to travel to Cambodia?▼
For travel to Cambodia, Routine vaccines, COVID-19, Hepatitis A, Hepatitis B, Measles and Typhoid are recommended; Chikungunya, Japanese Encephalitis, Rabies and Yellow Fever may be advised depending on your itinerary. Make sure your routine vaccinations (such as MMR, Tdap, polio and seasonal flu) are up to date, and see a travel-health provider about 4–6 weeks before you leave.
Is there malaria in Cambodia?▼
Yes — malaria is present in Cambodia. Antimalarial prophylaxis is recommended for most travelers, alongside insect-bite precautions such as repellent and treated bed nets.
Is it safe to travel to Cambodia?▼
From a travel-health standpoint, Cambodia is currently rated moderate risk. Cambodia carries a CDC Level 1 travel health notice. Malaria risk exists primarily in rural and forested areas of Cambodia. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
What are the emergency phone numbers in Cambodia?▼
Key emergency numbers in Cambodia are Police 117, Medical / Ambulance 119, Fire 118 and U.S. Embassy +855-23-728-000. Save them before you travel and confirm the current numbers with your accommodation on arrival.
More country guides
Brunei Darussalam carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine not needed from US, but required if coming from countries with yellow fever risk or long layovers there
Christmas Island carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Cocos (Keeling) Islands carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed for disease protection in Cocos Islands, but is required if you're coming from a country with yellow fever risk, including airport layovers over 12 hours. Direct travel from the US does not require vaccination.
Plan your Cambodia trip
Get vaccines, prescriptions and a personalized health plan for Cambodia — matched to your itinerary and travelers.
Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.